Letrozole – Its Uses And Side Effects
Letrozole is a treatment for breast cancers. It is a non-steroidal aromatase inhibitor used by patients with a type of breast cancer associated with hormones. This is usually prescribed to patients after surgery.
What are its uses?
The FDA has approved this drug in the treatment of metastatic, hormone-receptor breast cancer positive.
Women who have already received other anti-cancer treatments may also take advantage of this drug’s benefits.
It can also be used in treating breast cancer that has been locally advanced.
Doctors may also recommend it to patients with advanced breast cancer that worsens even after undergoing anti-estrogen therapy.
Currently, scientists are studying this drug’s other benefits and uses.
What are its off-label uses?
Apart from those benefits mentioned above, letrozole is also used by fertility doctors for ovarian stimulation to their patients. However, it was found out that this drug may cause potential risks to infants. Thus, it is important not to take it if you are pregnant.
It may promote spermatogenesis in male patients. But this is only effective if the case is of non-obstructive azoospermia.
How it works in breast cancer?
What this drug does is to prevent aromatase, which is an enzyme that converts androgen into estrogen. In this way, production of estrogen will be reduced. This drug reverses binding to the estrogen receptor which causes the breast cancer cells to die.
How to use it?
Before you start taking this drug, it is highly recommended that you read its leaflet.
You must only take it by mouth, once a day. It is important to follow what your doctor has prescribed, whether to take it with or without food.
Your response to treatment and your current medical condition are bases on the proper dosage of this drug.
To help you remember taking it each day, you must take it at the same time every day.
Although this drug is effective in treating your condition, you must inform your doctor if you feel that your condition has not changed or got worsen. That is, if you experience breast lumps.
Side effects you must know
Notify your doctor if you experience any of these side effects.
The majority of its users have not experienced serious side effects associated with this drug.
You must inform your doctor immediately if you have these side effects:
Swelling of the arms and/or legs
Immediate medical attention must be given if you experience these effects:
Shortness of breath
Coughing up of blood
Although these side effects are very unlikely, you must seek immediate medical attention if they do occur.
Where to purchase letrozole?
The products listed here are manufactured by WHO and GMP companies.